Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 6/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 5/20 | 0.36 |
| ▸ | MAPK12 | P53778 | 5/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079673 | 0.87 | MAPK13 (0.36) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 | |
| SCHEMBL7079671 | 0.87 | MAPK13 (0.36) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 | |
| SCHEMBL7080443 | 0.85 | MAPK14 (0.37) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 | |
| SCHEMBL7079266 | 0.85 | MAPK13 (0.47) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 | |
| SCHEMBL7076531 | 0.84 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 | |
| SCHEMBL7074437 | 0.84 | MAPK14 (0.54) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 | |
| SCHEMBL7074441 | 0.84 | MAPK14 (0.54) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 | |
| SCHEMBL7076530 | 0.84 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 | |
| SCHEMBL7080247 | 0.82 | SCN1A (0.38) | ALDH1A1GAAMAPTHPGDPRSS12 | |
| SCHEMBL7076728 | 0.82 | MAPK13 (0.45) | MAPK14MAPK13MAPK12MAPK11ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030073832-A1 | Novel aminophenyl ketone derivatives | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2003-04-17 | — | — | US | claimed |
| US-20030073832-A1 | Novel aminophenyl ketone derivatives | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2003-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073832-A1 | Novel aminophenyl ketone derivatives | MAPKAPK2, MAP3K2, MAP3K1 | MAPK14 28/4885MAPK13 33/4885MAPK12 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.