Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | ASPH | Q12797 | 6/20 | 0.42 |
| ▸ | KDM8 | Q8N371 | 6/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | AGER | Q15109 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027039 | 0.88 | KDM4E (0.42) | KDM4EASPHKDM8ATRALDH1A1 | |
| SCHEMBL28485640 | 0.84 | ATR (0.51) | KDM4EATRALDH1A1MAPTL3MBTL1 | |
| SCHEMBL6261311 | 0.83 | ATR (0.43) | KDM4EATRALDH1A1GRM6CA12 | |
| SCHEMBL3243857 | 0.81 | ATR (0.42) | KDM4EATRALDH1A1MAPTALOX15 | |
| SCHEMBL6671123 | 0.80 | ATR (0.53) | KDM4EATRALDH1A1GRM6LMNA | |
| SCHEMBL7080699 | 0.79 | GRM6 (0.41) | KDM4EASPHKDM8ATRALDH1A1 | |
| SCHEMBL22750385 | 0.79 | ATR (0.40) | KDM4EASPHKDM8ATRALDH1A1 | |
| SCHEMBL18159123 | 0.78 | KDM4E (0.60) | KDM4EASPHKDM8ALDH1A1MAPT | |
| SCHEMBL16515769 | 0.78 | KDM4E (0.61) | KDM4EALDH1A1MAPTL3MBTL1CYP3A4 | |
| SCHEMBL6255617 | 0.76 | ATR (0.37) | ATRALDH1A1MAPTALOX15GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4511375-A1 | BICYCLIC COMPOUNDS | Aligos Therapeutics, Inc. (US) | 2025-02-26 | — | — | EP | disclosed |
| WO-2023205653-A1 | BICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | disclosed |
| EP-0758328-B1 | ANTI-CANCER COMPOUNDS CONTAINING CYCLOPENTAQUINAZOLINE RING | BTG INT LTD (GB) | 2003-07-16 | — | — | EP | disclosed |
| EP-0667864-B1 | TRICYCLIC COMPOUNDS WITH PHARMACEUTICAL ACTIVITY | ZENECA LTD (GB) | 1997-09-24 | — | — | EP | disclosed |