Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28218776 | 0.77 | MEN1 (0.55) | MEN1KMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL7087493 | 0.76 | MEN1 (0.51) | MEN1KMT2A | |
| SCHEMBL27943924 | 0.76 | CYP2C9 (0.55) | MEN1KMT2ASMN1; SMN2TSHRCYP2C9 | |
| SCHEMBL31162708 | 0.75 | EPHX2 (0.47) | KMT2AALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7086564 | 0.74 | CYP2C9 (0.60) | MEN1KMT2ASMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL27597066 | 0.74 | CYP2C9 (0.50) | MEN1KMT2ACYP2C9CYP2C19MAPK14 | |
| SCHEMBL6132371 | 0.74 | HDAC3 (0.43) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL31162845 | 0.73 | MAPT (0.48) | KMT2AALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL6132226 | 0.73 | SPHK1 (0.42) | MEN1KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL31162587 | 0.73 | SCN9A (0.47) | ALDH1A1MAPTL3MBTL1HDAC1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003068807-A2 | ECHINOCANDIN CYCLIC PEPTIDE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-08-21 | — | — | WO | disclosed |