⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20211373 | 0.87 | — | — | |
| SCHEMBL7081966 | 0.86 | — | — | |
| SCHEMBL10479185 | 0.85 | — | — | |
| SCHEMBL9058041 | 0.83 | — | — | |
| SCHEMBL6182462 | 0.81 | — | — | |
| SCHEMBL430949 | 0.77 | — | — | |
| SCHEMBL14689909 | 0.74 | — | — | |
| SCHEMBL1289421 | 0.74 | MEN1 (0.32) | — | |
| SCHEMBL419805 | 0.74 | MEN1 (0.32) | — | |
| SCHEMBL8009 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1323727-A2 | Composition and methods for the synthesis of organophosphorus derivatives | GENTA INCORPORATED (US) | 2003-07-02 | — | — | EP | claimed |
| EP-1323727-A2 | Composition and methods for the synthesis of organophosphorus derivatives | GENTA INCORPORATED (US) | 2003-07-02 | — | — | EP | disclosed |
| US-5936080-A | Compositions and methods for the synthesis of organophosphorus derivatives | GENTA INCORPORATED (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0828749-A4 | COMPOSITIONS AND METHODS FOR THE SYNTHESIS OF ORGANOPHOSPHORUS DERIVATIVES | GENTA INC (US) | 1998-11-04 | — | — | EP | disclosed |
| EP-0828749-A1 | COMPOSITIONS AND METHODS FOR THE SYNTHESIS OF ORGANOPHOSPHORUS DERIVATIVES | GENTA INCORPORATED (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996037503-A1 | COMPOSITIONS AND METHODS FOR THE SYNTHESIS OF ORGANOPHOSPHORUS DERIVATIVES | GENTA INCORPORATED (US) | 1996-11-28 | — | — | WO | disclosed |