Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7076153 | 0.90 | MAPK14 (0.53) | ALDH1A1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7080366 | 0.90 | MAPK14 (0.45) | ALDH1A1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7080369 | 0.87 | MAPK14 (0.43) | ALDH1A1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7076774 | 0.87 | MAPK13 (0.37) | ALDH1A1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7077185 | 0.87 | MAPK13 (0.37) | ALDH1A1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7080479 | 0.86 | MAPK13 (0.50) | ALDH1A1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7080601 | 0.85 | KMT2A (0.44) | ALDH1A1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7081237 | 0.84 | MAPK13 (0.39) | ALDH1A1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7081240 | 0.84 | MAPK13 (0.39) | ALDH1A1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL7076675 | 0.79 | MAPK13 (0.47) | ALDH1A1MAPK13MAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030073832-A1 | Novel aminophenyl ketone derivatives | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2003-04-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073832-A1 | Novel aminophenyl ketone derivatives | MAPKAPK2, MAP3K2, MAP3K1 | ALDH1A1 1960/4885MAPK13 33/4885MAPK12 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.