Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT5B | Q4FZB7 | 2/20 | 0.54 |
| ▸ | KMT5C | Q86Y97 | 2/20 | 0.54 |
| ▸ | NSD2 | O96028 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6861719 | 0.90 | KMT5B (0.63) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6861714 | 0.90 | KMT5B (0.63) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6866595 | 0.89 | KMT5B (0.56) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6866590 | 0.89 | KMT5B (0.56) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6873014 | 0.85 | KMT5B (0.57) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6873010 | 0.85 | KMT5B (0.57) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6867709 | 0.82 | KMT5B (0.63) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6867708 | 0.82 | KMT5B (0.63) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6872817 | 0.82 | KMT5B (0.57) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6872815 | 0.82 | KMT5B (0.57) | KMT5BKMT5CNSD2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003070244-A1 | ANTAGONIST OF MELANIN CONCENTRATING HORMONE AND THEIR USES | ABBOTT LABORATORIES (US) | 2003-08-28 | — | — | WO | disclosed |