SCHEMBL7083086

SCHEMBL7083086

Nc1cccc(O)c1Nc1ccccc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 2/20 0.49
ALOX15 P16050 2/20 0.48
TSHR P16473 1/20 0.48
GAA P10253 9/20 0.41
MAPT P10636 5/20 0.41
LMNA P02545 4/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
KDM4E B2RXH2 3/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
KDM1A O60341 1/20 0.41
TTR P02766 1/20 0.40
HPGD P15428 2/20 0.38
BLM P54132 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TP53 P04637 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11554645 0.85 CXCR2 (0.57) CXCR2ALOX15GAAMAPTLMNA
SCHEMBL22584770 0.81 CXCR2 (0.53) CXCR2ALOX15GAAMAPTLMNA
SCHEMBL9118423 0.81 MAPT (0.56) CXCR2ALOX15TSHRGAAMAPT
Hydrochloric Acid SCHEMBL9121083 0.79 MAPT (0.54) CXCR2ALOX15TSHRGAAMAPT
SCHEMBL22169138 0.78 CXCR2 (0.50) CXCR2ALOX15TSHRGAAMAPT
SCHEMBL7051274 0.77 CXCR2 (0.42) CXCR2ALOX15TSHRGAAMAPT
SCHEMBL7588837 0.75 GAA (0.49) ALOX15GAAMAPTLMNAMEN1
SCHEMBL304891 0.75 CXCR2 (0.54) CXCR2ALOX15GAAMAPTLMNA
SCHEMBL10662151 0.73 TTR (0.55) CXCR2TSHRGAALMNAKMT2A
SCHEMBL1417442 0.73 CXCR2 (0.42) CXCR2ALOX15TSHRGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020120989-A1 OXIDATION HAIR DYEING AGENT COMPOSITION DOW CORNING CORPORATION 2002-09-05 US claimed
US-6432145-B1 Oxidation hair dyeing agent composition DOW CORNING CORPORATION 2002-08-13 US claimed
WO-2003066007-A1 HAIR CARE COMPOSITIONS CONTAINING POLYSILOXANES DOW CORNING CORPORATION (US) 2003-08-14 WO disclosed
US-20020120989-A1 OXIDATION HAIR DYEING AGENT COMPOSITION DOW CORNING CORPORATION 2002-09-05 US disclosed
US-6432145-B1 Oxidation hair dyeing agent composition DOW CORNING CORPORATION 2002-08-13 US disclosed