Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 20/20 | 0.71 |
| ▸ | RARB | P10826 | 18/20 | 0.71 |
| ▸ | RARA | P10276 | 17/20 | 0.71 |
| ▸ | RXRA | P19793 | 12/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.71 |
| ▸ | GMNN | O75496 | 1/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | TP53 | P04637 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | THPO | P40225 | 1/20 | 0.71 |
| ▸ | MTOR | P42345 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007206 | 1.00 | RARG (0.71) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL7083141 | 1.00 | RARG (0.71) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL11225183 | 0.91 | RARG (0.67) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL11503237 | 0.89 | RARG (0.68) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL7085845 | 0.87 | RARG (0.65) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL7085841 | 0.87 | RARG (0.65) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL11250453 | 0.87 | RARG (0.65) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL11213589 | 0.87 | RARG (0.65) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL10624409 | 0.86 | RARG (0.64) | RARGRARBRARARXRAKDM4E | |
| SCHEMBL10624389 | 0.86 | RARG (0.64) | RARGRARBRARARXRAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326055-A | ANTITUMOR AGENTS, SKIN DISORDERS, RHEUMATIC DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1982-04-20 | — | — | US | claimed |
| EP-0002742-A1 | Stilbene derivatives, their preparation and medicines containing these stilbene derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-07-11 | — | — | EP | claimed |
| EP-1328262-A2 | A METHOD TO INCORPORATE N-(4-HYDROXYPHENYL) RETINAMIDE IN LIPOSOMES | Board of Regents, The University of Texas System (US) | 2003-07-23 | — | — | EP | disclosed |
| US-20020143062-A1 | Method to incorporate N-(4-hydroxyphenyl) retinamide in liposomes | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2002-10-03 | — | — | US | disclosed |
| WO-2002032413-A2 | A METHOD TO INCORPORATE N-(4-HYDROXYPHENYL) RETINAMIDE IN LIPOSOMES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2002-04-25 | — | — | WO | disclosed |
| US-5534261-A | Retinoid-based compositions and method for preventing adhesion formation using the same | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0176050-B1 | PHOSPHORIC ACID VINYL BENZYL ESTERS, THEIR PREPARATION AND USE | BASF Aktiengesellschaft (DE) | 1989-01-25 | — | — | EP | disclosed |
| US-4659701-A | Vinylbenzyl phosphates, and their use for treating dermalogical disorders | BASF AKTIENGESELLSCHAFT (DE) | 1987-04-21 | — | — | US | disclosed |
| EP-0176050-A2 | Phosphoric acid vinyl benzyl esters, their preparation and use | BASF Aktiengesellschaft (DE) | 1986-04-02 | — | — | EP | disclosed |
| EP-0021339-B1 | SUGAR ESTERS AND GLYCOSIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-02-09 | — | — | EP | disclosed |
| US-4326055-A | ANTITUMOR AGENTS, SKIN DISORDERS, RHEUMATIC DISEASES | HOFFMANN-LA ROCHE INC. (US) | 1982-04-20 | — | — | US | disclosed |
| EP-0002742-B1 | STILBENE DERIVATIVES, THEIR PREPARATION AND MEDICINES CONTAINING THESE STILBENE DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-04-14 | — | — | EP | disclosed |
| US-4316983-A | Neoplasmic compounds: sugar esters and glycosides | HOFFMANN-LA ROCHE INC. (US) | 1982-02-23 | — | — | US | disclosed |
| EP-0021339-A1 | Sugar esters and glycosides, their preparation and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-01-07 | — | — | EP | disclosed |
| EP-0002742-A1 | Stilbene derivatives, their preparation and medicines containing these stilbene derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-07-11 | — | — | EP | disclosed |