Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.61 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.61 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.40 |
| ▸ | HTR5A | P47898 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HK1 | P19367 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13907678 | 0.81 | NPC1 (0.53) | BRD4CREBBPAHRPDK2NPC1 | |
| Hydrochloric Acid SCHEMBL19031500 | 0.79 | NPC1 (0.52) | BRD4CREBBPAHRPDK2NPC1 | |
| SCHEMBL27410535 | 0.78 | MAPT (0.47) | BRD4CREBBPAHRPDK2NPC1 | |
| SCHEMBL28355036 | 0.76 | BRD4 (0.61) | BRD4CREBBPAHRPDK2NPC1 | |
| SCHEMBL677636 | 0.76 | BRD4 (1.00) | BRD4CREBBPAHRPDK2NPC1 | |
| SCHEMBL13947064 | 0.76 | BRD4 (0.61) | BRD4CREBBPAHRPDK2NPC1 | |
| SCHEMBL3248383 | 0.74 | BRD4 (0.41) | BRD4CREBBPAHRPDK2HSP90AA1 | |
| SCHEMBL13806532 | 0.74 | PDE3B (0.41) | BRD4CREBBPCDK5CDK5R1 | |
| SCHEMBL13806309 | 0.74 | PDE3B (0.41) | BRD4CREBBPCDK5CDK5R1 | |
| SCHEMBL23119793 | 0.73 | MAPT (0.58) | BRD4CREBBPAHRPDK2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2065382-A1 | CGRP antagonists | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2009-06-03 | — | — | EP | disclosed |
| WO-2009050235-A1 | CGRP ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-04-23 | — | — | WO | disclosed |
| EP-0987255-B1 | Substituted aminoquinazolinone (thione) derivatives | NIHON NOHYAKU CO LTD (JP) | 2003-07-16 | — | — | EP | disclosed |
| CN-1112848-C | Pest controlling agent containing substituted aminoquinazolone or thioketone derivative or its salt as active component | NIHON NOHYAKU CO LTD (JP) | 2003-07-02 | — | — | CN | disclosed |
| JP-2003104985-A | METHOD FOR PRODUCING QUINAZOLINE DERIVATIVE | NIPPON NOHYAKU CO LTD | 2003-04-09 | — | — | JP | disclosed |
| CN-1092188-C | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest control agents and methods of using the same | NIHON NOHYAKU CO LTD (JP) | 2002-10-09 | — | — | CN | disclosed |
| EP-0735035-B1 | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest controllers and a method for using the same | NIHON NOHYAKU CO LTD (JP) | 2002-06-05 | — | — | EP | disclosed |
| EP-0987255-A2 | Substituted aminoquinazolinone (thione) derivatives | NIHON NOHYAKU CO., LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5714492-A | INSECTICIDES | NIHON NOHYAKU CO., LTD. (JP) | 1998-02-03 | — | — | US | disclosed |
| CN-1134933-A | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest control agents and methods of using the same | NIHON NOHYAKU CO LTD (JP) | 1996-11-06 | — | — | CN | disclosed |
| EP-0735035-A1 | Substituted aminoquinazolinone (thione) derivatives or salts thereof, intermediates thereof, and pest controllers and a method for using the same | NIHON NOHYAKU CO., LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |