Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.62 |
| ▸ | FNTB | P49356 | 2/20 | 0.62 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570064 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL7575956 | 0.93 | — | — | |
| SCHEMBL7574823 | 0.89 | FNTA (0.76) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7576334 | 0.89 | FNTA (0.75) | FNTAFNTBPGGT1B | |
| SCHEMBL7571142 | 0.84 | PGGT1B (0.71) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7577316 | 0.84 | PGGT1B (0.70) | FNTAFNTBPGGT1B | |
| SCHEMBL7094457 | 0.82 | PGGT1B (0.75) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7575771 | 0.81 | PGGT1B (0.74) | FNTAFNTBPGGT1B | |
| SCHEMBL7571029 | 0.81 | — | — | |
| SCHEMBL7568471 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276726-A2 | SUBSTITUTED PHENYL FARNESYLTRANSFERASE INHIBITORS | Abbott Laboratories (US) | 2003-01-22 | — | — | EP | disclosed |
| WO-2001081316-A2 | SUBSTITUTED PHENYL FARNESYLTRANSFERASE INHIBITORS | ABBOTT LABORATORIES (US) | 2001-11-01 | — | — | WO | disclosed |