Benzene

Benzene

SCHEMBL7084450

CC(C)c1cccc(C(C)C)c1.c1ccccc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 2/20 0.54
HDAC8 Q9BY41 2/20 0.54
KDM4E B2RXH2 2/20 0.54
ALDH1A1 P00352 2/20 0.54
ALOX12 P18054 2/20 0.54
HTT P42858 2/20 0.54
MDM4 O15151 1/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
TP53 P04637 1/20 0.54
CYP3A4 P08684 1/20 0.54
MAPT P10636 1/20 0.54
TYR P14679 1/20 0.54
HPGD P15428 1/20 0.54
ALOX15 P16050 1/20 0.54
CA5A P35218 1/20 0.54
MDM2 Q00987 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
CA9 Q16790 1/20 0.54
HDAC2 Q92769 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Peroxide SCHEMBL28407249 0.97 HDAC4 (0.58) HDAC4HDAC8KDM4EALDH1A1ALOX12
Hydrogen Peroxide SCHEMBL315899 0.97 HDAC4 (0.58) HDAC4HDAC8KDM4EALDH1A1ALOX12
Hydrogen Peroxide SCHEMBL1877668 0.97 HDAC4 (0.58) HDAC4HDAC8KDM4EALDH1A1ALOX12
SCHEMBL374780 0.97 HDAC4 (0.56) HDAC4HDAC8KDM4EALDH1A1ALOX12
Methyl Alcohol SCHEMBL9619051 0.94 HDAC4 (0.56) HDAC4HDAC8KDM4EALDH1A1ALOX12
SCHEMBL11036540 0.94 HDAC4 (0.54) HDAC4HDAC8KDM4EALDH1A1ALOX12
SCHEMBL31122172 0.94 HDAC4 (0.54) HDAC4HDAC8KDM4EALDH1A1ALOX12
Hydrochloric Acid SCHEMBL28429663 0.94 HDAC4 (0.54) HDAC4HDAC8KDM4EALDH1A1ALOX12
Water SCHEMBL9322811 0.94 HDAC4 (0.54) HDAC4HDAC8KDM4EALDH1A1ALOX12
SCHEMBL19031518 0.94 KDM4E (0.54) HDAC4HDAC8KDM4EALDH1A1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1062191-B1 ALKYLAROMATICS PRODUCTION EXXONMOBIL OIL CORP (US) 2003-07-23 EP disclosed