Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 18/20 | 1.00 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | IDH2 | P48735 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088324 | 0.93 | SERPINE1 (1.00) | SERPINE1NOTUMIDH2 | |
| SCHEMBL7085542 | 0.88 | SERPINE1 (0.93) | SERPINE1 | |
| SCHEMBL7091010 | 0.83 | SERPINE1 (1.00) | SERPINE1 | |
| SCHEMBL7084140 | 0.78 | SERPINE1 (0.64) | SERPINE1NOTUM | |
| SCHEMBL30173256 | 0.77 | NOTUM (0.85) | SERPINE1NOTUMIDH2 | |
| SCHEMBL4334462 | 0.77 | NOTUM (0.85) | SERPINE1NOTUMIDH2 | |
| SCHEMBL7088252 | 0.76 | SERPINE1 (0.77) | SERPINE1 | |
| SCHEMBL7084790 | 0.76 | SERPINE1 (0.60) | SERPINE1NOTUMIDH2 | |
| SCHEMBL7091079 | 0.75 | SERPINE1 (1.00) | SERPINE1 | |
| SCHEMBL7088122 | 0.75 | SERPINE1 (0.59) | SERPINE1NOTUMIDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080060-A1 | SUBSTITUTED PIPERAZINE ANTITHROMBOTIC PAI-1 INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |