Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459990 | 0.81 | TDP1 (0.39) | TDP1 | |
| SCHEMBL9130929 | 0.79 | TDP1 (0.37) | TDP1 | |
| SCHEMBL13822372 | 0.79 | TDP1 (0.37) | TDP1 | |
| SCHEMBL9131612 | 0.71 | TDP1 (0.30) | TDP1 | |
| SCHEMBL13392802 | 0.70 | TDP1 (0.46) | TDP1 | |
| SCHEMBL9391499 | 0.70 | TSHR (0.31) | — | |
| SCHEMBL4912736 | 0.69 | TDP1 (0.36) | TDP1 | |
| SCHEMBL13822519 | 0.69 | — | — | |
| SCHEMBL6691952 | 0.68 | TDP1 (0.30) | TDP1 | |
| SCHEMBL7086407 | 0.67 | KDM4E (0.36) | KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030108495-A1 | Cosmetic compositions containing 2,2-dihydroxymethy1-1,3-dioxolanes | STROUD ERIC MATTHEW (US) | 2003-06-12 | — | — | US | disclosed |