Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 20/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 11/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.60 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987392 | 1.00 | ADRB3 (0.60) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL6074081 | 0.89 | ADRB3 (0.75) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| Hydrochloric Acid SCHEMBL6074156 | 0.89 | ADRB3 (0.74) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL6074690 | 0.87 | ADRB3 (0.67) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL6074731 | 0.83 | ADRB3 (0.70) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL6074253 | 0.83 | ADRB3 (0.63) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL6074855 | 0.81 | ADRB3 (0.61) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL7225278 | 0.81 | ADRB3 (0.60) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL7530132 | 0.79 | ADRB3 (0.74) | ADRB3ADRB1ADRB2ADRA2AADRA2B | |
| SCHEMBL7117049 | 0.78 | ADRB3 (0.73) | ADRB3ADRB1ADRB2ADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328512-A2 | CYCLYLAMINE SULFONAMIDES AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | Wyeth (US) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002006221-A2 | CYCLYLAMINE SULFONAMIDES AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |