Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 16/20 | 0.88 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085638 | 0.94 | SERPINE1 (0.84) | SERPINE1NR4A2LMNAMAPTHTT | |
| SCHEMBL7085685 | 0.94 | SERPINE1 (1.00) | SERPINE1LMNAMAPTHTTL3MBTL1 | |
| SCHEMBL7088370 | 0.91 | SERPINE1 (0.77) | SERPINE1LMNAMAPTHTTL3MBTL1 | |
| SCHEMBL7089529 | 0.89 | SERPINE1 (0.75) | SERPINE1LMNAMAPTHTTL3MBTL1 | |
| SCHEMBL7088218 | 0.86 | SERPINE1 (1.00) | SERPINE1LMNAMAPTHTTL3MBTL1 | |
| SCHEMBL7090405 | 0.83 | SERPINE1 (0.80) | SERPINE1LMNAMAPTHTTL3MBTL1 | |
| SCHEMBL7084984 | 0.83 | SERPINE1 (0.79) | SERPINE1LMNAMAPTHTTL3MBTL1 | |
| SCHEMBL7091114 | 0.82 | SERPINE1 (0.77) | SERPINE1LMNAMAPTHTTL3MBTL1 | |
| SCHEMBL7088416 | 0.79 | SERPINE1 (0.59) | SERPINE1NR4A2RXRARXRBRXRG | |
| SCHEMBL7087929 | 0.79 | SERPINE1 (0.67) | SERPINE1LMNAMAPTHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003080060-A1 | SUBSTITUTED PIPERAZINE ANTITHROMBOTIC PAI-1 INHIBITORS | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-02 | — | — | WO | disclosed |