Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT5B | Q4FZB7 | 2/20 | 0.53 |
| ▸ | KMT5C | Q86Y97 | 2/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | WNK1 | Q9H4A3 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869796 | 0.93 | KMT5B (0.54) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6869795 | 0.93 | KMT5B (0.54) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6867916 | 0.87 | KMT5B (0.58) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6867912 | 0.87 | KMT5B (0.58) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6869551 | 0.84 | KMT5B (0.55) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6869556 | 0.84 | KMT5B (0.55) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6867240 | 0.84 | KMT5B (0.57) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6867243 | 0.84 | KMT5B (0.57) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6866553 | 0.83 | KMT5B (0.61) | KMT5BKMT5CNSD2CYP2D6CYP2C19 | |
| SCHEMBL6866551 | 0.83 | KMT5B (0.61) | KMT5BKMT5CNSD2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003070244-A1 | ANTAGONIST OF MELANIN CONCENTRATING HORMONE AND THEIR USES | ABBOTT LABORATORIES (US) | 2003-08-28 | — | — | WO | disclosed |