Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.49 |
| ▸ | MAOA | P21397 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | CALML3 | P27482 | 1/20 | 0.45 |
| ▸ | SDHA | P31040 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | F10 | P00742 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087265 | 0.88 | MAOB (0.46) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL27441524 | 0.84 | MAOB (0.66) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL27441526 | 0.84 | MAOB (0.66) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL27535189 | 0.84 | CALML3 (0.53) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7161231 | 0.83 | MAOB (0.64) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7161232 | 0.83 | MAOB (0.64) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL5105550 | 0.82 | KCNH2 (0.61) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL5105553 | 0.82 | KCNH2 (0.61) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL7091406 | 0.81 | MAOB (0.55) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL27571175 | 0.80 | MAOB (0.60) | MAOBMAOALMNAPTGS1CALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106454-A1 | 1H-ISOQUINOLINE-OXAZOLIDINONE DERIVATIES AND THEIR USE AS ANTIBACTERIAL AGENTS | ORCHID CHEMICALS & PHARMACEUTICALS LTD (IN) | 2003-12-24 | — | — | WO | disclosed |