Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5477951 | 0.86 | NISCH (0.73) | NISCHPOLBCASP6SMN1; SMN2HPGD | |
| Potassium Ion SCHEMBL11364654 | 0.84 | NISCH (0.61) | NISCHPOLBCASP6SMN1; SMN2HPGD | |
| SCHEMBL9327125 | 0.83 | POLB (0.56) | NISCHPOLBCASP6SMN1; SMN2HPGD | |
| SCHEMBL7490172 | 0.82 | NISCH (0.58) | NISCHPOLBCASP6HPGDTSHR | |
| Hydrochloric Acid SCHEMBL9751989 | 0.81 | POLB (0.55) | NISCHPOLBCASP6SMN1; SMN2HPGD | |
| SCHEMBL11453649 | 0.79 | NISCH (0.51) | NISCHPOLBCASP6SMN1; SMN2HPGD | |
| SCHEMBL7487260 | 0.78 | NISCH (0.54) | NISCHPOLBSMN1; SMN2TSHRKDM4E | |
| SCHEMBL29606554 | 0.78 | POLB (0.69) | NISCHPOLBCASP6SMN1; SMN2HPGD | |
| SCHEMBL2547829 | 0.78 | POLB (0.69) | NISCHPOLBCASP6SMN1; SMN2HPGD | |
| Dimethylamine SCHEMBL9752837 | 0.77 | POLB (0.50) | NISCHPOLBCASP6SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4281012-A | HYPOLIPEMIC ACTIVITY | ROUSSEL UCLAF (FR) | 1981-07-28 | — | — | US | claimed |
| EP-0018675-A2 | Lipogenesis inhibiting composition and process for its preparation | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-11-12 | — | — | EP | claimed |
| EP-0018674-A1 | Benzodioxincarboxylic acid derivatives, their preparation and their inclusion in lipogenesis inhibiting compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-11-12 | — | — | EP | claimed |
| US-11874601-B2 | Resist composition, method of forming resist pattern, compound, and acid diffusion-controlling agent | TOKYO OHKA KOGYO CO., LTD. (JP) | 2024-01-16 | — | — | US | disclosed |
| US-11874601-B2 | Resist composition, method of forming resist pattern, compound, and acid diffusion-controlling agent | TOKYO OHKA KOGYO CO., LTD. (JP) | 2024-01-16 | — | — | US | disclosed |
| US-20220011665-A1 | RESIST COMPOSITION, METHOD OF FORMING RESIST PATTERN, COMPOUND, AND ACID DIFFUSION-CONTROLLING AGENT | TOKYO OHKA KOGYO CO., LTD. (JP) | 2022-01-13 | — | — | US | disclosed |
| EP-2850070-B1 | BENZO[1,3]DIOXINE DERIVATIVES AND THEIR USE AS LPAR5 ANTAGONISTS | SANOFI SA (FR) | 2017-08-23 | — | — | EP | disclosed |
| US-9221784-B2 | Benzo[1,3]dioxine derivatives and their use as LPAR5 antagonists | SANOFI (FR) | 2015-12-29 | — | — | US | disclosed |
| US-20150111889-A1 | Benzo[1,3]Dioxine Derivatives And Their Use As LPAR5 Antagonists | SANOFI (FR) | 2015-04-23 | — | — | US | disclosed |
| EP-2850070-A1 | BENZO[1,3]DIOXINE DERIVATIVES AND THEIR USE AS LPAR5 ANTAGONISTS | SANOFI (FR) | 2015-03-25 | — | — | EP | disclosed |
| WO-2013171318-A1 | BENZO[1,3]DIOXINE DERIVATIVES AND THEIR USE AS LPAR5 ANTAGONISTS | SANOFI (FR) | 2013-11-21 | — | — | WO | disclosed |
| US-4281012-A | HYPOLIPEMIC ACTIVITY | ROUSSEL UCLAF (FR) | 1981-07-28 | — | — | US | disclosed |
| US-4281012-A | HYPOLIPEMIC ACTIVITY | ROUSSEL UCLAF (FR) | 1981-07-28 | — | — | US | disclosed |
| US-4281012-A | HYPOLIPEMIC ACTIVITY | ROUSSEL UCLAF (FR) | 1981-07-28 | — | — | US | disclosed |
| EP-0018674-A1 | Benzodioxincarboxylic acid derivatives, their preparation and their inclusion in lipogenesis inhibiting compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-11-12 | — | — | EP | disclosed |
| EP-0018675-A2 | Lipogenesis inhibiting composition and process for its preparation | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-11-12 | — | — | EP | disclosed |
| EP-0018675-A2 | Lipogenesis inhibiting composition and process for its preparation | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-11-12 | — | — | EP | disclosed |
| EP-0018674-A1 | Benzodioxincarboxylic acid derivatives, their preparation and their inclusion in lipogenesis inhibiting compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-11-12 | — | — | EP | disclosed |
| EP-0018674-A1 | Benzodioxincarboxylic acid derivatives, their preparation and their inclusion in lipogenesis inhibiting compositions | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-11-12 | — | — | EP | disclosed |
| US-4217360-A | LUTEOLYTIC | SCHERING AKTIENGESELLSCHAFT (DE) | 1980-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150111889-A1 | Benzo[1,3]Dioxine Derivatives And Their Use As LPAR5 Antagonists | LPAR5, LPAR1, LPAR2 | NISCH 2893/4885POLB 4730/4885CASP6 3294/4885 |
| US-20220011665-A1 | RESIST COMPOSITION, METHOD OF FORMING RESIST PATTERN, COMPOUND, AND ACID DIFFUSION-CONTROLLING AGENT | MRPS23, MRPS22, SLC11A2 | NISCH 3746/4885POLB 1693/4885CASP6 3361/4885 |
| US-11874601-B2 | Resist composition, method of forming resist pattern, compound, and acid diffusion-controlling agent | MRPS23, MRPS22, SLC11A2 | NISCH 3783/4885POLB 1789/4885CASP6 3394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.