Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 13/20 | 1.00 |
| ▸ | HCRTR1 | O43613 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | GPR183 | P32249 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6325198 | 0.91 | HCRTR2 (1.00) | HCRTR2HCRTR1KMT2ANPC1KDM4E | |
| SCHEMBL6326967 | 0.88 | HCRTR2 (0.79) | HCRTR2HCRTR1KMT2ANPC1KDM4E | |
| SCHEMBL6428456 | 0.82 | HCRTR2 (0.76) | HCRTR2HCRTR1KMT2ANPC1KDM4E | |
| SCHEMBL6324543 | 0.81 | HCRTR2 (0.75) | HCRTR2HCRTR1KMT2ANPC1KDM4E | |
| SCHEMBL6332961 | 0.79 | HCRTR2 (0.70) | HCRTR2HCRTR1KMT2ANPC1KDM4E | |
| SCHEMBL18766747 | 0.79 | HCRTR2 (0.70) | HCRTR2HCRTR1KMT2ANPC1KDM4E | |
| SCHEMBL6324675 | 0.78 | HCRTR2 (0.76) | HCRTR2HCRTR1KMT2ANPC1KDM4E | |
| SCHEMBL6326677 | 0.78 | HCRTR2 (0.76) | HCRTR2HCRTR1KMT2ANPC1KDM4E | |
| SCHEMBL6326918 | 0.78 | HCRTR2 (0.76) | HCRTR2HCRTR1KMT2ANPC1KDM4E | |
| SCHEMBL5022449 | 0.76 | HCRTR2 (0.66) | HCRTR2HCRTR1KMT2ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1288202-A1 | N-ACYLTETRAHYDROISOQUINOLINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2003-03-05 | — | — | EP | disclosed |