Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695646 | 0.93 | POLA1 (0.54) | POLA1KCNH2MEN1KMT2AABCB1 | |
| SCHEMBL6698552 | 0.88 | POLA1 (0.51) | POLA1KCNH2MEN1KMT2AABCB1 | |
| SCHEMBL7590247 | 0.83 | POLA1 (0.60) | POLA1KCNH2MEN1KMT2AABCB1 | |
| SCHEMBL6699742 | 0.82 | POLA1 (0.59) | POLA1KCNH2MEN1KMT2AABCB1 | |
| SCHEMBL7590238 | 0.81 | POLA1 (0.61) | POLA1KCNH2MEN1KMT2AABCB1 | |
| SCHEMBL6697394 | 0.81 | POLA1 (0.59) | POLA1KCNH2MEN1KMT2AABCB1 | |
| SCHEMBL6695445 | 0.81 | POLA1 (0.61) | POLA1KCNH2MEN1KMT2AABCB1 | |
| SCHEMBL6696316 | 0.81 | POLA1 (0.53) | POLA1KCNH2MEN1KMT2AABCB1 | |
| SCHEMBL6694266 | 0.80 | POLA1 (0.54) | POLA1KCNH2MEN1KMT2AABCB1 | |
| SCHEMBL6693410 | 0.80 | POLA1 (0.54) | POLA1KCNH2MEN1KMT2AABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265873-B1 | 4-OXO-1,4-DIHYDRO-3-CINNOLINECARBOXAMIDES AS ANTIVIRAL AGENTS | UPJOHN CO (US) | 2003-10-15 | — | — | EP | claimed |