Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.43 |
| ▸ | F2 | P00734 | 6/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAT | P00750 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087191 | 0.94 | F10 (0.44) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7132692 | 0.93 | F10 (0.45) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7088476 | 0.93 | F10 (0.44) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7089325 | 0.91 | F10 (0.41) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7087677 | 0.91 | F10 (0.40) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7084486 | 0.90 | F10 (0.41) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7083383 | 0.89 | F10 (0.42) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7090126 | 0.89 | F10 (0.47) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7083866 | 0.89 | F10 (0.45) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7089277 | 0.88 | F10 (0.40) | F10PRSS1F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294720-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096338-A1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-12-20 | — | — | WO | disclosed |