Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 20/20 | 0.54 |
| ▸ | EDNRB | P24530 | 11/20 | 0.54 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | DHPS | P49366 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968460 | 0.96 | EDNRA (0.55) | EDNRAEDNRBABCC3ABCC4NR1I2 | |
| SCHEMBL6972398 | 0.95 | EDNRA (0.51) | EDNRAEDNRBABCC3ABCC4NR1I2 | |
| SCHEMBL7086528 | 0.94 | EDNRA (0.49) | EDNRAEDNRBABCC3ABCC4NR1I2 | |
| SCHEMBL6965528 | 0.94 | EDNRA (0.60) | EDNRAEDNRBABCC3ABCC4NR1I2 | |
| SCHEMBL7085973 | 0.93 | EDNRA (0.64) | EDNRAEDNRB | |
| SCHEMBL7085774 | 0.92 | EDNRA (0.50) | EDNRAEDNRBABCC3ABCC4NR1I2 | |
| SCHEMBL6972166 | 0.90 | EDNRA (0.48) | EDNRAEDNRBABCC3ABCC4NR1I2 | |
| SCHEMBL6959738 | 0.89 | EDNRA (0.67) | EDNRAEDNRBABCC3ABCC4NR1I2 | |
| SCHEMBL7085443 | 0.88 | EDNRA (0.65) | EDNRAEDNRB | |
| SCHEMBL6956778 | 0.88 | EDNRA (0.51) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0799209-B1 | SULFONAMIDES | HOFFMANN LA ROCHE (CH) | 2003-08-06 | — | — | EP | claimed |