Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | METAP2 | P50579 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PNLIP | P16233 | 1/20 | 0.54 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.54 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.54 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083823 | 0.90 | POLB (0.61) | GAAPOLBNPC1RAB9AKDM4E | |
| SCHEMBL7084141 | 0.87 | GAA (0.57) | GAAPOLBNPC1RAB9AKDM4E | |
| SCHEMBL31393767 | 0.87 | GAA (0.89) | GAAPOLBNPC1RAB9AKDM4E | |
| SCHEMBL8715012 | 0.87 | GAA (0.89) | GAAPOLBNPC1RAB9AKDM4E | |
| SCHEMBL7132902 | 0.86 | GAA (0.87) | GAAPOLBNPC1RAB9AKDM4E | |
| SCHEMBL7303620 | 0.82 | GAA (0.76) | GAAPOLBNPC1RAB9AKDM4E | |
| SCHEMBL6300807 | 0.80 | GAA (0.80) | GAAPOLBNPC1RAB9AKDM4E | |
| SCHEMBL7080611 | 0.79 | GAA (0.62) | GAAPOLBNPC1RAB9AKDM4E | |
| SCHEMBL6680203 | 0.78 | PLAU (0.46) | GAAPOLBNPC1RAB9AMEN1 | |
| SCHEMBL3018085 | 0.77 | PLAU (0.61) | GAAPOLBNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |