Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 14/20 | 1.00 |
| ▸ | FNTB | P49356 | 14/20 | 1.00 |
| ▸ | PGGT1B | P53609 | 5/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.85 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2287583 | 0.92 | FNTA (1.00) | FNTAFNTBPGGT1BCYP3A4NR1H4 | |
| SCHEMBL29387865 | 0.87 | FNTA (1.00) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6975755 | 0.87 | FNTA (1.00) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL7084213 | 0.87 | FNTA (0.88) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL27500775 | 0.87 | FNTA (0.84) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6977397 | 0.85 | FNTA (0.84) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL7084114 | 0.83 | FNTA (0.86) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6978930 | 0.81 | FNTA (1.00) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6600154 | 0.80 | FNTA (0.66) | FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL6607629 | 0.79 | FNTA (0.75) | FNTAFNTBPGGT1BCYP3A4NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1045846-B1 | IMIDAZOLE DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2003-05-02 | — | — | EP | claimed |
| US-6472526-B1 | SHOWS AN INHIBITORY ACTIVITY AGAINST FARNESYL TRANSFERASE OR PHARMACEUTICALLY ACCEPTABLE SALTS OR ISOMERS THEREOF, IN PHARMACEUTICAL COMPOSITION AND INTERMEDIATES | LG CHEMICAL LTD. (KR) | 2002-10-29 | — | — | US | disclosed |