Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086336 | 1.00 | HCAR2 (0.45) | HCAR2ESR1ESR2GAALMNA | |
| SCHEMBL4596466 | 0.87 | ESR1 (0.43) | ESR1ESR2GAALMNACYP3A4 | |
| SCHEMBL17868323 | 0.86 | HCAR2 (0.51) | HCAR2GAALMNACA12CA1 | |
| SCHEMBL10339832 | 0.86 | HCAR2 (0.51) | HCAR2GAALMNACA12CA1 | |
| SCHEMBL10339833 | 0.86 | HCAR2 (0.51) | HCAR2GAALMNACA12CA1 | |
| SCHEMBL1592408 | 0.84 | GAA (0.47) | ESR1ESR2GAALMNACYP3A4 | |
| SCHEMBL6552314 | 0.84 | ESR1 (0.45) | ESR1ESR2GAALMNACYP3A4 | |
| SCHEMBL3677313 | 0.82 | KDM4E (0.52) | ESR1ESR2GAALMNACYP3A4 | |
| SCHEMBL1837900 | 0.81 | ESR1 (0.42) | ESR1ESR2GAALMNACYP3A4 | |
| SCHEMBL9818570 | 0.81 | GAA (0.45) | ESR1ESR2GAALMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1331494-A1 | COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL, AND PLASTIC LENS | NOF CORPORATION (JP) | 2003-07-30 | — | — | EP | disclosed |