Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087606 | 1.00 | BDKRB1 (0.55) | BDKRB1TP53LMNAMAPTHTT | |
| SCHEMBL6982382 | 0.94 | BDKRB1 (0.55) | BDKRB1TP53LMNAMAPTALDH1A1 | |
| SCHEMBL6763334 | 0.91 | BDKRB1 (0.58) | BDKRB1TP53LMNAMAPTHTT | |
| SCHEMBL6763335 | 0.91 | BDKRB1 (0.58) | BDKRB1TP53LMNAMAPTHTT | |
| SCHEMBL6982375 | 0.89 | BDKRB1 (0.58) | BDKRB1TP53LMNAMAPTHTT | |
| SCHEMBL6881504 | 0.88 | BDKRB1 (0.69) | BDKRB1TP53LMNAMAPTHTT | |
| SCHEMBL6763313 | 0.86 | BDKRB1 (0.67) | BDKRB1TP53LMNAMAPTHTT | |
| SCHEMBL6760041 | 0.86 | BDKRB1 (0.65) | BDKRB1TP53LMNAMAPTHTT | |
| SCHEMBL6763310 | 0.86 | BDKRB1 (0.67) | BDKRB1TP53LMNAMAPTHTT | |
| SCHEMBL6760039 | 0.86 | BDKRB1 (0.65) | BDKRB1TP53LMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351928-A2 | NOVEL N(PHENYLSULPHONYL)GLYCINE DERIVATIVES AND THEIR THERAPEUTIC USE | LABORATOIRES FOURNIER S.A. (FR) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002053516-A2 | N(PHENYLSULPHONYL)GLYCINE DERIVATIVES AND THEIR THERAPEUTIC USE | LABORATOIRES FOURNIER SA (FR) | 2002-07-11 | — | — | WO | disclosed |