Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 18/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7656524 | 0.95 | ADORA2A (0.69) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7222636 | 0.91 | ADORA2A (0.74) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7084921 | 0.89 | ADORA2A (0.67) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7763687 | 0.89 | ADORA2A (0.69) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7088171 | 0.89 | ADORA2A (0.69) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL5086172 | 0.89 | ADORA2A (0.71) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7087538 | 0.88 | ADORA2A (0.70) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7089191 | 0.88 | ADORA2A (0.68) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7089485 | 0.88 | ADORA2A (0.70) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL7135983 | 0.88 | ADORA2A (0.70) | ADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090022-B1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-08-06 | — | — | EP | claimed |
| US-6495528-B1 | ANTIINFLAMMATORY AGENTS; INHIBITING LEUKOCYTE RECRUITMENT AND ACTIVATION; AGONISTS OF ADENOSINE 2A RECEPTOR | SMITHKLINE BEECHAM CORPORATION | 2002-12-17 | — | — | US | claimed |
| EP-1090022-A1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2001-04-11 | — | — | EP | claimed |
| WO-1999067265-A1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-12-29 | — | — | WO | claimed |
| EP-1090022-B1 | 2-(PURIN-9-YL)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2003-08-06 | — | — | EP | disclosed |