Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153011 | 0.81 | TDP1 (0.46) | MAPTNPC1KDM4ES1PR4S1PR1 | |
| SCHEMBL7084589 | 0.79 | TDP1 (0.45) | MAPTNPC1KDM4ES1PR4S1PR1 | |
| SCHEMBL1138440 | 0.76 | TDP1 (0.41) | MAPTNPC1KDM4ES1PR4S1PR1 | |
| SCHEMBL292398 | 0.71 | CYP1A2 (0.40) | MAPTKDM4EHTTRAB9ATSHR | |
| SCHEMBL12712555 | 0.71 | TDP1 (0.54) | MAPTNPC1KDM4ES1PR4S1PR1 | |
| SCHEMBL4574563 | 0.70 | CYP3A4 (0.55) | MAPTNPC1RAB9ANPSR1TSHR | |
| SCHEMBL249714 | 0.69 | TDP1 (0.52) | TSHRTDP1HSD17B10HPRT1CTSB | |
| SCHEMBL6245129 | 0.69 | HPRT1 (0.78) | MAPTNPC1KDM4ES1PR4S1PR1 | |
| SCHEMBL9652405 | 0.68 | HTT (0.45) | MAPTKDM4EHTTHSD17B10ALDH1A1 | |
| SCHEMBL9806470 | 0.68 | CYP1A2 (0.46) | MAPTKDM4EHTTNPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010082-A | Fungicides, microbiocides | CIBA-GEIGY CORPORATION (US) | 1991-04-23 | — | — | US | claimed |
| EP-0362135-A2 | Parasiticide | CIBA-GEIGY AG (CH) | 1990-04-04 | — | — | EP | claimed |
| US-6639070-B1 | 4-substituted 1,3,4-oxadiazines; herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2003-10-28 | — | — | US | disclosed |
| EP-1187819-B1 | N-SUBSTITUTED PERHYDRO DIAZINE | BASF AG (DE) | 2003-07-23 | — | — | EP | disclosed |
| CN-1364161-A | N-substituted perhydrodiazines | BASF AG (DE) | 2002-08-14 | — | — | CN | disclosed |
| US-5010082-A | Fungicides, microbiocides | CIBA-GEIGY CORPORATION (US) | 1991-04-23 | — | — | US | disclosed |
| EP-0362135-A2 | Parasiticide | CIBA-GEIGY AG (CH) | 1990-04-04 | — | — | EP | disclosed |