SCHEMBL7088893

SCHEMBL7088893

C=CCOC(=O)[N]C(=N)N

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.42
CACNA1B Q00975 1/20 0.42
APBA1 Q02410 1/20 0.42
CYP3A4 P08684 1/20 0.36
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.35
HSD17B10 Q99714 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL729015 0.83 CYP3A4 (0.43) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL7088896 0.75 MAPT (0.44) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL1345378 0.73 CYP3A4 (0.43) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL527276 0.73 CYP3A4 (0.43) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL11607297 0.72
Guanidine SCHEMBL171536 0.72 MAPT (0.46) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL9547228 0.72 MAPT (0.42) MAPTCACNA1BAPBA1CYP3A4TSHR
SCHEMBL19033480 0.72
SCHEMBL10940301 0.72
SCHEMBL8671962 0.71 MAPT (0.36) MAPTCACNA1BAPBA1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003068807-A2 ECHINOCANDIN CYCLIC PEPTIDE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-08-21 WO disclosed