Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.30 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28193190 | 0.98 | HSD17B10 (0.31) | HSD17B10 | |
| SCHEMBL1855601 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL11546148 | 0.84 | HTR2A (0.34) | — | |
| Toluene SCHEMBL27992273 | 0.83 | HSD17B10 (0.39) | HSD17B10TSHRLMNASMN1; SMN2 | |
| SCHEMBL15198721 | 0.80 | — | — | |
| SCHEMBL14222286 | 0.80 | KDM4E (0.35) | — | |
| SCHEMBL12286788 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL31404655 | 0.78 | KDM4E (0.34) | — | |
| SCHEMBL6913918 | 0.77 | CYP1A2 (0.31) | — | |
| SCHEMBL659895 | 0.75 | NPSR1 (0.37) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107474049-A | One kind (±) different maca thiocarbamide B bio-mimetic syntheses preparation method | 云南民族大学 | 2017-12-15 | — | — | CN | claimed |
| EP-2834221-B1 | CYCLIC AMIDES AS METAP-2 INHIBITORS | MERCK PATENT GMBH (DE) | 2016-05-25 | — | — | EP | claimed |
| JP-54046785-A | — | — | None | — | — | JP | disclosed |
| CN-107474049-A | One kind (±) different maca thiocarbamide B bio-mimetic syntheses preparation method | 云南民族大学 | 2017-12-15 | — | — | CN | disclosed |
| US-20030143729-A1 | DNA encoding taurine and GABA transporters and uses thereof | SYNAPTIC PHARMACEUTICAL CORPORATION | 2003-07-31 | — | — | US | disclosed |
| US-6225115-B1 | DNA encoding taurine and GABA transporters and uses thereof | SYNAPTIC PHARMACEUTICAL CORPORATION | 2001-05-01 | — | — | US | disclosed |
| EP-0678028-A4 | DNA ENCODING A HUMAN BETAINE/GABA TRANSPORTER AND USES THEREOF. | SYNAPTIC PHARMA CORP (US) | 1999-10-20 | — | — | EP | disclosed |
| US-5766848-A | RECEPTOR BINDING ASSAY TO DETECT COMPOUND BOUND TO BETAINE/G-AMINOBUTYRIC ACID TRANSPORTER EXPRESSED ON SURFACE OF NONNEURONAL CELLS | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1998-06-16 | — | — | US | disclosed |
| US-5712148-A | GAMMA-AMINOBUTYRIC ACID, VECTORS, PLASMIDS | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1998-01-27 | — | — | US | disclosed |
| US-5658786-A | ISOLATED NUCLEIC ACID | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0631623-A4 | DNA ENCODING TAURINE AND GABA TRANSPORTERS AND USES THEREOF. | SYNAPTIC PHARMA CORP (US) | 1996-09-25 | — | — | EP | disclosed |
| WO-1996004790-A1 | DNA ENCODING A HUMAN BETAINE/GABA TRANSPORTER AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1996-02-22 | — | — | WO | disclosed |
| EP-0678028-A1 | DNA ENCODING A HUMAN BETAINE/GABA TRANSPORTER AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1995-10-25 | — | — | EP | disclosed |
| EP-0631623-A1 | DNA ENCODING TAURINE AND GABA TRANSPORTERS AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1995-01-04 | — | — | EP | disclosed |
| WO-1994015618-A1 | DNA ENCODING A HUMAN BETAINE/GABA TRANSPORTER AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1994-07-21 | — | — | WO | disclosed |
| WO-1993018143-A1 | DNA ENCODING TAURINE AND GABA TRANSPORTERS AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1993-09-16 | — | — | WO | disclosed |
| EP-0001280-B1 | 1-N-ACYLATED-4-O-GLYCOSYL-6-O-GLYCOSYL-1,3-DIAMINOCYCLITOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SHIONOGI & CO., LTD. (JP) | 1981-11-25 | — | — | EP | disclosed |
| US-4199570-A | AZETIDINE, PYRROLIDINE, OR PIPERIDINE | SHIONOGI & CO., LTD. (JP) | 1980-04-22 | — | — | US | disclosed |
| JP-S5446785-A | NOVEL AMINOGLYCOSIDE DERIVATIVE | SHIONOGI & CO LTD | 1979-04-12 | — | — | JP | disclosed |
| EP-0001280-A2 | 1-N-acylated-4-O-glycosyl-6-O-glycosyl-1,3-diaminocyclitol derivatives, process for their preparation and pharmaceutical compositions containing them | SHIONOGI & CO., LTD. (JP) | 1979-04-04 | — | — | EP | disclosed |