Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656880 | 0.95 | TACR1 (0.84) | TACR1 | |
| SCHEMBL7090516 | 0.93 | TACR1 (0.82) | TACR1 | |
| SCHEMBL7088905 | 0.93 | TACR1 (0.86) | TACR1 | |
| SCHEMBL7085269 | 0.93 | TACR1 (0.88) | TACR1 | |
| SCHEMBL7088608 | 0.93 | TACR1 (0.86) | TACR1 | |
| SCHEMBL7089798 | 0.92 | TACR1 (0.84) | TACR1 | |
| SCHEMBL7088790 | 0.92 | TACR1 (0.87) | TACR1 | |
| SCHEMBL7088019 | 0.91 | TACR1 (0.86) | TACR1 | |
| SCHEMBL7088172 | 0.91 | TACR1 (1.00) | TACR1 | |
| SCHEMBL7088638 | 0.91 | TACR1 (0.88) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1005454-A4 | 2-ACYLAMINOPROPANAMINES AS TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2003-01-15 | — | — | EP | disclosed |
| US-6358994-B1 | 2-((2-PHENOXY)ACETYL)AMINO-3-(1H-INDOL-3-YL)-1-(N-2 -METHOXYBENZYL)ACETYLAMINO)PROPANE | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |
| EP-1005454-A1 | 2-ACYLAMINOPROPANAMINES AS TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2000-06-07 | — | — | EP | disclosed |
| WO-1999007677-A1 | 2-ACYLAMINOPROPANAMINES AS TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1999-02-18 | — | — | WO | disclosed |