SCHEMBL7090656

SCHEMBL7090656

[CH]1CC=CC=C1P(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2304866 0.73 CYP3A4 (0.63) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL7633395 0.72 CYP3A4 (0.60) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL1158074 0.67 TDP1 (0.92) CYP3A4TDP1ESR1ESR2KDM4E
Hydrochloric Acid SCHEMBL23273899 0.65 CYP3A4 (0.44) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL22208885 0.65 CYP3A4 (0.44) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL31070079 0.65 CYP3A4 (0.44) CYP3A4TDP1ESR1ESR2KDM4E
SCHEMBL10276789 0.64 TDP1 (0.86) CYP3A4TDP1ESR1ESR2KDM4E
Potassium Ion SCHEMBL28768622 0.64 TDP1 (0.86) CYP3A4TDP1ESR1ESR2KDM4E
Water SCHEMBL27450403 0.64 TDP1 (0.86) CYP3A4TDP1ESR1ESR2KDM4E
Hydrochloric Acid SCHEMBL27388633 0.64 TDP1 (0.86) CYP3A4TDP1ESR1ESR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101314608-A Bidentate organophosphor ligand and uses thereof EVONIK DEGUSSA AG (DE) 2008-12-03 CN disclosed
US-6573389-B1 As catalysts for asymmetric reaction or polymerization DEGUSSA AG (DE) 2003-06-03 US disclosed