SCHEMBL7090727

SCHEMBL7090727

C=C(C)C(=O)Nc1nc2ccccc2s1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 P30542 2/20 0.72
DYRK1A Q13627 1/20 0.72
NPC1 O15118 8/20 0.60
RAB9A P51151 8/20 0.60
SMN1; SMN2 Q16637 5/20 0.60
KMT2A Q03164 4/20 0.60
MEN1 O00255 3/20 0.60
GAA P10253 3/20 0.60
CYP1A2 P05177 1/20 0.60
NFKB1 P19838 3/20 0.58
NFKB2 Q00653 3/20 0.58
RELA Q04206 3/20 0.58
MAPT P10636 3/20 0.58
ALDH1A1 P00352 5/20 0.58
LMNA P02545 2/20 0.57
TP53 P04637 1/20 0.57
HPGD P15428 1/20 0.57
HSD17B10 Q99714 1/20 0.57
CSNK1D P48730 2/20 0.56
POLB P06746 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13076639 0.84 ADORA1 (0.71) ADORA1DYRK1ANPC1RAB9ASMN1; SMN2
SCHEMBL3283083 0.84 DYRK1A (1.00) ADORA1DYRK1ANPC1RAB9ASMN1; SMN2
SCHEMBL3054828 0.83 NPC1 (0.69) ADORA1DYRK1ANPC1RAB9ASMN1; SMN2
SCHEMBL10094297 0.81 DYRK1A (0.74) ADORA1DYRK1ANPC1RAB9ASMN1; SMN2
SCHEMBL6476095 0.81 ADORA1 (0.71) ADORA1DYRK1ANPC1RAB9ASMN1; SMN2
SCHEMBL32674581 0.80 NPC1 (0.84) ADORA1DYRK1ANPC1RAB9ASMN1; SMN2
SCHEMBL27634788 0.80 NPC1 (0.84) ADORA1DYRK1ANPC1RAB9ASMN1; SMN2
SCHEMBL11160903 0.80 ADORA1 (0.65) ADORA1DYRK1ANPC1RAB9ASMN1; SMN2
SCHEMBL5211562 0.79 ADORA1 (0.73) ADORA1DYRK1ANPC1RAB9ASMN1; SMN2
SCHEMBL1580942 0.79 NPC1 (0.73) ADORA1DYRK1ANPC1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0164807-B1 MULTIFUNCTIONAL ADDITIVE FOR LUBRIFICATING OILS AND PROCESS FOR THE PREPARATION THEREOF AGIP PETROLI S.p.A. (IT) 1989-10-18 EP claimed
US-4618439-A GRAFT POLYMER OF ACRYLIC ESTER AGIP PETROLI S.P.A. (IT) 1986-10-21 US claimed
EP-0164807-A2 Multifunctional additive for lubrificating oils and process for the preparation thereof AGIP PETROLI S.p.A. (IT) 1985-12-18 EP claimed
CN-114907514-A Multifunctional fiber and preparation method and application thereof 北京洁尔爽高科技有限公司 2022-08-16 CN disclosed
EP-0854388-B1 Negative-type image recording materials FUJI PHOTO FILM CO LTD (JP) 2003-08-13 EP disclosed
US-6068963-A CONTAINS (A) A POLYMER HAVING A HETEROCYCLIC GROUP CONTAINING AN UNSATURATED BOND THEREIN, (B) A CROSS-LINKING AGENT THAT CROSS-LINKS WITH THE AID OF AN ACID, AND (C) A COMPOUND THAT GENERATES AN ACID UPON EXPOSURE TO LIGHT OR HEAT. FUJI PHOTO FILM CO., LTD. (JP) 2000-05-30 US disclosed
EP-0854388-A2 Negative-type image recording materials FUJI PHOTO FILM CO., LTD. (JP) 1998-07-22 EP disclosed
EP-0164807-B1 MULTIFUNCTIONAL ADDITIVE FOR LUBRIFICATING OILS AND PROCESS FOR THE PREPARATION THEREOF AGIP PETROLI S.p.A. (IT) 1989-10-18 EP disclosed
US-4618439-A GRAFT POLYMER OF ACRYLIC ESTER AGIP PETROLI S.P.A. (IT) 1986-10-21 US disclosed
EP-0164807-A2 Multifunctional additive for lubrificating oils and process for the preparation thereof AGIP PETROLI S.p.A. (IT) 1985-12-18 EP disclosed