SCHEMBL7090739

SCHEMBL7090739

Cc1ccccc1-c1cc([C@@H](OCc2ccc(C(C)C)cc2)c2cncn2C)ccc1C#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7090743 1.00
Hydrochloric Acid SCHEMBL7569973 0.99
SCHEMBL7577050 0.94
SCHEMBL7569317 0.94
SCHEMBL7571844 0.94
Hydrochloric Acid SCHEMBL7568863 0.94
Hydrochloric Acid SCHEMBL7568955 0.93
Hydrochloric Acid SCHEMBL7569945 0.93
SCHEMBL7572051 0.93
SCHEMBL7577195 0.93 FNTA (0.80)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1276726-A2 SUBSTITUTED PHENYL FARNESYLTRANSFERASE INHIBITORS Abbott Laboratories (US) 2003-01-22 EP disclosed
WO-2001081316-A2 SUBSTITUTED PHENYL FARNESYLTRANSFERASE INHIBITORS ABBOTT LABORATORIES (US) 2001-11-01 WO disclosed