Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.72 |
| ▸ | FNTB | P49356 | 1/20 | 0.72 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7569375 | 0.99 | FNTA (0.71) | FNTAFNTBPGGT1B | |
| SCHEMBL7570221 | 0.92 | FNTA (0.73) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7091561 | 0.91 | FNTA (0.72) | FNTAFNTBPGGT1B | |
| SCHEMBL7090444 | 0.89 | PGGT1B (0.90) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7572408 | 0.88 | PGGT1B (0.89) | FNTAFNTBPGGT1B | |
| SCHEMBL7084936 | 0.86 | FNTA (0.77) | FNTAFNTBPGGT1B | |
| SCHEMBL7577050 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL7577108 | 0.85 | FNTA (0.76) | FNTAFNTBPGGT1B | |
| SCHEMBL7091753 | 0.85 | PGGT1B (0.68) | FNTAFNTBPGGT1B | |
| Hydrochloric Acid SCHEMBL7568863 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1276726-A2 | SUBSTITUTED PHENYL FARNESYLTRANSFERASE INHIBITORS | Abbott Laboratories (US) | 2003-01-22 | — | — | EP | disclosed |
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | ABBOTT LABORATORIES | 2002-02-14 | — | — | US | disclosed |
| WO-2001081316-A2 | SUBSTITUTED PHENYL FARNESYLTRANSFERASE INHIBITORS | ABBOTT LABORATORIES (US) | 2001-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | FNTA, FNTB, SLC10A1 | FNTA 1/4885FNTB 2/4885PGGT1B 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.