Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL953066 | 0.92 | TSHR (0.48) | TSHRTDP1HPGDHCAR2CYP3A4 | |
| SCHEMBL18095147 | 0.92 | TSHR (0.48) | TSHRTDP1HPGDHCAR2CYP3A4 | |
| SCHEMBL47912 | 0.85 | CYP3A4 (0.45) | TSHRSOAT1TDP1HPGDCYP3A4 | |
| SCHEMBL21233305 | 0.85 | TSHR (0.44) | TSHRTDP1HPGDHCAR2CYP3A4 | |
| SCHEMBL7096132 | 0.83 | SOAT1 (0.65) | TSHRSOAT1TDP1HPGDHCAR2 | |
| SCHEMBL9110969 | 0.83 | CYP3A4 (0.43) | TSHRSOAT1TDP1HPGDCYP3A4 | |
| SCHEMBL2497149 | 0.82 | SOAT1 (0.60) | TSHRSOAT1TDP1HPGDHCAR2 | |
| SCHEMBL7260853 | 0.81 | TSHR (0.44) | TSHRTDP1HPGDHCAR2CYP3A4 | |
| SCHEMBL28139259 | 0.80 | MEN1 (0.42) | TSHRTDP1HPGDHCAR2CYP3A4 | |
| SCHEMBL7267486 | 0.80 | TSHR (0.57) | TSHRTDP1HPGDHCAR2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586135-B2 | Dicarbonate compound such as dibenzyl dicarbonate mixed with either the anode material or the cathode active material prior to contact with its current collector | WILSON GREATBACH LTD. | 2003-07-01 | — | — | US | claimed |
| EP-0951085-B1 | Dicarbonate additives for non-aqueous electrolyte in alkali metal electrochemical cells | GREATBATCH W LTD (US) | 2003-01-29 | — | — | EP | claimed |
| US-20020136949-A1 | Electrochemical cell having an electrode with a dicarbonate additive in the electrode active mixture | GREATBATCH, INC. | 2002-09-26 | — | — | US | claimed |
| EP-1244159-A1 | Electrochemical cell having an electrode with a dicarbonate additive in the electrode active mixture | WILSON GREATBATCH LTD. (US) | 2002-09-25 | — | — | EP | claimed |
| US-6174629-B1 | ADDITION OF AT LEAST ONE DICARBONATE ADDITIVE TO AN ELECTROLYTE COMPRISING AN ALKALI METAL SALT DISSOLVED IN A SOLVENT MIXTURE THAT INCLUDES ETHYLENE CARBONATE, DIMETHYL CARBONATE, ETHYL METHYL CARBONATE AND DIETHYL CARBONATE | WILSON GREATBATCH LTD. | 2001-01-16 | — | — | US | claimed |
| EP-1005098-A2 | Alkali metal electrochemical cell having an improved cathode activated with a nonaqueous electrolyte having a passivation inhibitor additive | WILSON GREATBATCH LTD. (US) | 2000-05-31 | — | — | EP | claimed |
| US-6063526-A | AN ALKALI METAL, SOLID CATHODE, NONAQUEOUS ELECTROCHEMICAL CELL CAPABLE OF DELIVERING HIGH CURRENT PULSES, RAPIDLY RECOVERING ITS OPEN CIRCUIT VOLTAGE AND HAVING HIGH CURRENT CAPACITY; USE IN MEDICAL DEVICES SUCH AS DEFIBRILLATORS | WILSON GREATBATCH LTD. (US) | 2000-05-16 | — | — | US | claimed |
| EP-0951085-A1 | Dicarbonate additives for non-aqueous electrolyte in alkali metal electrochemical cells | WILSON GREATBATCH LTD. (US) | 1999-10-20 | — | — | EP | claimed |
| US-6586135-B2 | Dicarbonate compound such as dibenzyl dicarbonate mixed with either the anode material or the cathode active material prior to contact with its current collector | WILSON GREATBACH LTD. | 2003-07-01 | — | — | US | disclosed |
| EP-0951085-B1 | Dicarbonate additives for non-aqueous electrolyte in alkali metal electrochemical cells | GREATBATCH W LTD (US) | 2003-01-29 | — | — | EP | disclosed |
| US-20020136949-A1 | Electrochemical cell having an electrode with a dicarbonate additive in the electrode active mixture | GREATBATCH, INC. | 2002-09-26 | — | — | US | disclosed |
| EP-1244159-A1 | Electrochemical cell having an electrode with a dicarbonate additive in the electrode active mixture | WILSON GREATBATCH LTD. (US) | 2002-09-25 | — | — | EP | disclosed |
| US-6221534-B1 | CATHODE IS INORGANIC REACTION PRODUCT CONTAINING VANADIUM OXIDE AND SILVER OXIDE | WILSON GREATBATCH LTD. | 2001-04-24 | — | — | US | disclosed |
| US-6174629-B1 | ADDITION OF AT LEAST ONE DICARBONATE ADDITIVE TO AN ELECTROLYTE COMPRISING AN ALKALI METAL SALT DISSOLVED IN A SOLVENT MIXTURE THAT INCLUDES ETHYLENE CARBONATE, DIMETHYL CARBONATE, ETHYL METHYL CARBONATE AND DIETHYL CARBONATE | WILSON GREATBATCH LTD. | 2001-01-16 | — | — | US | disclosed |
| EP-1005098-A2 | Alkali metal electrochemical cell having an improved cathode activated with a nonaqueous electrolyte having a passivation inhibitor additive | WILSON GREATBATCH LTD. (US) | 2000-05-31 | — | — | EP | disclosed |
| US-6063526-A | AN ALKALI METAL, SOLID CATHODE, NONAQUEOUS ELECTROCHEMICAL CELL CAPABLE OF DELIVERING HIGH CURRENT PULSES, RAPIDLY RECOVERING ITS OPEN CIRCUIT VOLTAGE AND HAVING HIGH CURRENT CAPACITY; USE IN MEDICAL DEVICES SUCH AS DEFIBRILLATORS | WILSON GREATBATCH LTD. (US) | 2000-05-16 | — | — | US | disclosed |
| EP-0951085-A1 | Dicarbonate additives for non-aqueous electrolyte in alkali metal electrochemical cells | WILSON GREATBATCH LTD. (US) | 1999-10-20 | — | — | EP | disclosed |