Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 13/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 5/20 | 0.54 |
| ▸ | HTR3B | O95264 | 5/20 | 0.54 |
| ▸ | HTR3A | P46098 | 5/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 5/20 | 0.54 |
| ▸ | HTR3C | Q8WXA8 | 5/20 | 0.54 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095326 | 1.00 | CHRNA7 (0.54) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7093174 | 0.90 | CHRNA7 (0.55) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7006176 | 0.90 | CHRNA7 (0.55) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5073039 | 0.88 | CHRNA7 (0.68) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5076055 | 0.88 | CHRNA7 (0.68) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5072901 | 0.88 | CHRNA7 (0.68) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6999116 | 0.88 | CHRNA7 (0.53) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5076027 | 0.88 | CHRNA7 (0.56) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5075135 | 0.88 | CHRNA7 (0.56) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5072526 | 0.87 | CHRNA7 (0.53) | CHRNA7HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259508-B1 | NOVEL BIARYLCARBOXAMIDES | ASTRAZENECA AB (SE) | 2003-10-15 | — | — | EP | claimed |