Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | RARB | P10826 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088434 | 0.95 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8428808 | 0.95 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7088350 | 0.94 | NPC1 (0.38) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7091331 | 0.94 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7089034 | 0.93 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7064581 | 0.93 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8428820 | 0.89 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8428768 | 0.88 | RARB (0.42) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL7557738 | 0.88 | RARB (0.42) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8426232 | 0.87 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0868501-B1 | PROCESS FOR CONTROLLING CONE TILT ANGLE IN MIXTURES OF SMECTIC LIQUID CRYSTAL COMPOUNDS | MINNESOTA MINING & MFG (US) | 2003-08-13 | — | — | EP | disclosed |
| US-5928562-A | HAVING EXTENDED HYDROCARBON ETHER GROUP ADJACENT TO A TERMINAL FLUOROALKYL OR FLUOROETHER GROUP; LOW VISCOSITY; HIGH SPEED RESPONSE; BRIGHTNESS; COMMPATIBILITY; DISPLAYS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1999-07-27 | — | — | US | disclosed |
| US-5658491-A | CONTROLLING BRIGHTNESS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-08-19 | — | — | US | disclosed |