Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 11/20 | 0.66 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.46 |
| ▸ | TUBB | P07437 | 3/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7002457 | 1.00 | KDM1A (0.66) | KDM1AMAOAMAOBALDH1A1TUBB4A | |
| SCHEMBL7002459 | 1.00 | KDM1A (0.66) | KDM1AMAOAMAOBALDH1A1TUBB4A | |
| SCHEMBL7092215 | 0.84 | KDM1A (0.72) | KDM1AMAOAMAOBTUBB4ATUBB | |
| SCHEMBL6996729 | 0.84 | KDM1A (0.72) | KDM1AMAOAMAOBTUBB4ATUBB | |
| SCHEMBL6996727 | 0.84 | KDM1A (0.72) | KDM1AMAOAMAOBTUBB4ATUBB | |
| SCHEMBL7002848 | 0.81 | KDM1A (0.68) | KDM1AMAOAMAOBTUBB4ATUBB | |
| SCHEMBL7002844 | 0.81 | KDM1A (0.68) | KDM1AMAOAMAOBTUBB4ATUBB | |
| SCHEMBL7092495 | 0.81 | KDM1A (0.68) | KDM1AMAOAMAOBTUBB4ATUBB | |
| SCHEMBL30630927 | 0.79 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL27440827 | 0.79 | KDM1A (1.00) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996621-B1 | TRIAZOLO[4,5-d]PYRIMIDINE DERIVATIVES AS ANTI-THROMBOTIC AGENTS | ASTRAZENECA AB (SE) | 2003-10-01 | — | — | EP | disclosed |
| EP-0996621-A1 | NOVEL COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 2000-05-03 | — | — | EP | disclosed |
| WO-1999005143-A1 | NOVEL COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1999-02-04 | — | — | WO | disclosed |