Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 19/20 | 0.59 |
| ▸ | MC5R | P33032 | 3/20 | 0.54 |
| ▸ | MC3R | P41968 | 3/20 | 0.54 |
| ▸ | MC1R | Q01726 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14356092 | 1.00 | MC4R (0.59) | MC4RMC5RMC3RMC1R | |
| SCHEMBL14356093 | 0.84 | MC4R (0.62) | MC4RMC5RMC3RMC1R | |
| SCHEMBL5331894 | 0.79 | MC4R (0.58) | MC4RMC3RMC1R | |
| SCHEMBL14355908 | 0.79 | MC4R (0.58) | MC4RMC3RMC1R | |
| SCHEMBL1920106 | 0.79 | MC4R (0.68) | MC4RMC5RMC3RMC1R | |
| SCHEMBL14356082 | 0.78 | MC4R (0.51) | MC4RMC5RMC3R | |
| SCHEMBL14356076 | 0.78 | MC4R (0.51) | MC4RMC5RMC3R | |
| SCHEMBL7095030 | 0.77 | MC4R (0.69) | MC4RMC5RMC3RMC1R | |
| SCHEMBL14356073 | 0.77 | MC4R (0.53) | MC4RMC5RMC3RMC1R | |
| SCHEMBL5336017 | 0.77 | MC4R (0.53) | MC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368340-A1 | PIPERAZINE DERIVATIVES AS MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002059108-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-08-01 | — | — | WO | disclosed |