SCHEMBL7092952

SCHEMBL7092952

Cc1cc(C)cc(C2CC2N)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 15/20 0.48
KDM1B Q8NB78 3/20 0.48
MAOB P27338 11/20 0.46
MAOA P21397 8/20 0.46
CYP2C19 P33261 4/20 0.46
CYP2B6 P20813 3/20 0.46
KCNH2 Q12809 3/20 0.46
RCOR1 Q9UKL0 3/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2D6 P10635 2/20 0.46
CYP2C9 P11712 2/20 0.46
LMNA P02545 2/20 0.46
TAAR1 Q96RJ0 2/20 0.46
CYP3A4 P08684 1/20 0.46
HTR1A P08908 1/20 0.46
ADRA2A P08913 1/20 0.46
CYP2A6 P11509 1/20 0.46
SLC6A2 P23975 1/20 0.46
HTR2C P28335 1/20 0.46
ADRA1A P35348 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7000209 1.00 KDM1A (0.48) KDM1AKDM1BMAOBMAOACYP2C19
SCHEMBL7000211 1.00 KDM1A (0.48) KDM1AKDM1BMAOBMAOACYP2C19
SCHEMBL7002711 0.78 HTR2C (0.61) KDM1AKDM1BMAOBMAOACYP2C19
SCHEMBL7002709 0.78 HTR2C (0.61) KDM1AKDM1BMAOBMAOACYP2C19
SCHEMBL7092556 0.78 HTR2C (0.61) KDM1AKDM1BMAOBMAOACYP2C19
SCHEMBL15235891 0.75 KDM1A (0.60) KDM1AKDM1BMAOBMAOACYP2C19
SCHEMBL5729182 0.75 KDM1A (0.60) KDM1AKDM1BMAOBMAOACYP2C19
SCHEMBL7093867 0.75 KDM1A (0.60) KDM1AKDM1BMAOBMAOACYP2C19
SCHEMBL18459253 0.75 KDM1A (0.60) KDM1AKDM1BMAOBMAOACYP2C19
SCHEMBL5729180 0.75 KDM1A (0.60) KDM1AKDM1BMAOBMAOACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0996621-B1 TRIAZOLO[4,5-d]PYRIMIDINE DERIVATIVES AS ANTI-THROMBOTIC AGENTS ASTRAZENECA AB (SE) 2003-10-01 EP disclosed