Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET3 | O43151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | FBXL19 | Q6PCT2 | 1/20 | 0.30 |
| ▸ | CXXC5 | Q7LFL8 | 1/20 | 0.30 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.30 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.30 |
| ▸ | CXXC4 | Q9H2H0 | 1/20 | 0.30 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663368 | 0.80 | NAMPT (0.31) | — | |
| SCHEMBL5766997 | 0.78 | — | — | |
| SCHEMBL17763731 | 0.69 | TET3 (0.30) | TET3KMT2AFBXL19CXXC5TET1 | |
| SCHEMBL18446067 | 0.68 | TET3 (0.32) | TET3KMT2AFBXL19CXXC5TET1 | |
| SCHEMBL5186884 | 0.68 | TET3 (0.33) | TET3KMT2AFBXL19CXXC5TET1 | |
| SCHEMBL5766992 | 0.68 | MEN1 (0.34) | KMT2A | |
| SCHEMBL13276144 | 0.67 | TET3 (0.31) | TET3KMT2AFBXL19CXXC5TET1 | |
| SCHEMBL6097168 | 0.67 | TET3 (0.33) | TET3KMT2AFBXL19CXXC5TET1 | |
| SCHEMBL17239284 | 0.66 | SCN9A (0.33) | KMT2A | |
| SCHEMBL15882153 | 0.66 | SCN9A (0.33) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286967-A1 | CYCLOHEXANE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LTD. (GB) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001087838-A1 | CYCLOHEXANE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS | MERCK SHARP & DOHME LIMITED (GB) | 2001-11-22 | — | — | WO | disclosed |