Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | DTYMK | P23919 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL787115 | 1.00 | TSHR (0.62) | TSHRTDP1L3MBTL1DTYMKCASP6 | |
| SCHEMBL12494511 | 0.88 | TSHR (0.57) | TSHRTDP1L3MBTL1DTYMKCASP6 | |
| SCHEMBL28308570 | 0.88 | TSHR (0.53) | TSHRTDP1L3MBTL1DTYMKCASP6 | |
| SCHEMBL27448270 | 0.86 | TSHR (0.62) | TSHRTDP1L3MBTL1DTYMKCASP6 | |
| SCHEMBL6304256 | 0.85 | TSHR (0.71) | TSHRTDP1L3MBTL1DTYMKCASP6 | |
| SCHEMBL30527937 | 0.84 | TSHR (0.64) | TSHRTDP1L3MBTL1DTYMKCASP6 | |
| SCHEMBL1585078 | 0.84 | TDP1 (0.64) | TSHRTDP1L3MBTL1DTYMKCASP6 | |
| SCHEMBL28842429 | 0.84 | TSHR (0.69) | TSHRTDP1L3MBTL1DTYMKCASP6 | |
| SCHEMBL28461063 | 0.84 | TSHR (0.64) | TSHRTDP1L3MBTL1DTYMKCASP6 | |
| SCHEMBL28162054 | 0.84 | TSHR (0.69) | TSHRTDP1L3MBTL1DTYMKCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763026-B1 | GASTRIN AND CCK ANTAGONISTS | BLACK JAMES FOUNDATION (GB) | 2003-03-26 | — | — | EP | disclosed |
| US-5912260-A | GASTRIC ACID SECRETION | JAMES BLACK FOUNDATION LIMITED (GB) | 1999-06-15 | — | — | US | disclosed |
| EP-0763026-A1 | GASTRIN AND CCK ANTAGONISTS | JAMES BLACK FOUNDATION LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995032949-A1 | GASTRIN AND CCK ANTAGONISTS | JAMES BLACK FOUNDATION LIMITED (GB) | 1995-12-07 | — | — | WO | disclosed |