Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 15/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5344785 | 0.87 | HRH2 (0.69) | HRH2HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL5345679 | 0.86 | HRH2 (0.69) | HRH2HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL5346295 | 0.76 | HRH2 (0.58) | HRH2HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL6779387 | 0.75 | HRH2 (0.77) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6779996 | 0.74 | HRH2 (0.79) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6781670 | 0.73 | HRH2 (0.79) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL4062870 | 0.73 | HRH2 (0.63) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5347801 | 0.73 | HRH2 (0.85) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6779707 | 0.73 | HRH2 (0.90) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5349798 | 0.72 | HRH2 (1.00) | HRH2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330453-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | Almirall Prodesfarma, S.A. (ES) | 2003-07-30 | — | — | EP | claimed |
| WO-2002036589-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA S.A. (ES) | 2002-05-10 | — | — | WO | claimed |
| EP-1330453-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | Almirall Prodesfarma, S.A. (ES) | 2003-07-30 | — | — | EP | disclosed |
| WO-2002036589-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA S.A. (ES) | 2002-05-10 | — | — | WO | disclosed |