Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 12/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | DPP4 | P27487 | 3/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.46 |
| ▸ | TUBB | P07437 | 4/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.46 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7868679 | 1.00 | KDM1A (0.63) | KDM1AMAOAMAOBDPP4TUBB4A | |
| SCHEMBL7094484 | 1.00 | KDM1A (0.63) | KDM1AMAOAMAOBDPP4TUBB4A | |
| SCHEMBL7092495 | 0.86 | KDM1A (0.68) | KDM1AMAOAMAOBDPP4TUBB4A | |
| SCHEMBL7002848 | 0.86 | KDM1A (0.68) | KDM1AMAOAMAOBDPP4TUBB4A | |
| SCHEMBL7002844 | 0.86 | KDM1A (0.68) | KDM1AMAOAMAOBDPP4TUBB4A | |
| SCHEMBL6996729 | 0.85 | KDM1A (0.72) | KDM1AMAOAMAOBTUBB4ATUBB | |
| SCHEMBL7092215 | 0.85 | KDM1A (0.72) | KDM1AMAOAMAOBTUBB4ATUBB | |
| SCHEMBL6996727 | 0.85 | KDM1A (0.72) | KDM1AMAOAMAOBTUBB4ATUBB | |
| SCHEMBL6997477 | 0.79 | HTR2A (0.59) | KDM1AMAOAMAOB | |
| SCHEMBL12971950 | 0.79 | HTR2A (0.59) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0996621-B1 | TRIAZOLO[4,5-d]PYRIMIDINE DERIVATIVES AS ANTI-THROMBOTIC AGENTS | ASTRAZENECA AB (SE) | 2003-10-01 | — | — | EP | disclosed |