Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.49 |
| ▸ | PPARA | Q07869 | 9/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318984 | 0.85 | PPARG (0.68) | PPARGPPARACYP1A2CYP3A4ABCB11 | |
| SCHEMBL7094948 | 0.84 | PPARA (0.49) | PPARGPPARACYP1A2CYP3A4ABCB11 | |
| SCHEMBL1549069 | 0.83 | PPARA (0.51) | PPARGPPARACYP1A2CYP3A4ABCB11 | |
| SCHEMBL25304637 | 0.81 | PPARA (0.46) | PPARGPPARACYP1A2CYP3A4ABCB11 | |
| SCHEMBL4575316 | 0.81 | PPARA (0.51) | PPARGPPARACYP1A2CYP3A4ABCB11 | |
| SCHEMBL1586472 | 0.80 | PPARA (0.54) | PPARGPPARALMNA | |
| SCHEMBL3484260 | 0.80 | PPARG (0.47) | PPARGPPARACYP1A2CYP3A4ABCB11 | |
| SCHEMBL1549155 | 0.80 | CYP4F2 (0.47) | PPARGPPARACYP1A2CYP3A4ABCB11 | |
| SCHEMBL6543925 | 0.80 | PPARA (0.45) | PPARGPPARACYP1A2CYP3A4ABCB11 | |
| SCHEMBL6081148 | 0.80 | MEN1 (0.49) | PPARGPPARACYP1A2CYP3A4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030032671-A1 | Propionic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2003-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030032671-A1 | Propionic acid derivatives | PPARD, PPARA, PPARG | PPARG 3/4885PPARA 2/4885CYP1A2 2538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.