Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8049132 | 0.79 | MME (0.57) | CYP2D6CYP2C19CPA1ALDH1A1MME | |
| SCHEMBL8049130 | 0.79 | MME (0.57) | CYP2D6CYP2C19CPA1ALDH1A1MME | |
| SCHEMBL9516214 | 0.75 | GRIK1 (0.47) | CYP2C19GRIK1GRIK2CPA1MME | |
| SCHEMBL4795102 | 0.72 | GRIK1 (0.62) | CYP2C19GRIK1GRIK2CPA1ALDH1A1 | |
| SCHEMBL7305997 | 0.72 | GRIK1 (0.62) | CYP2C19GRIK1GRIK2CPA1ALDH1A1 | |
| SCHEMBL1885655 | 0.72 | GRIK1 (0.62) | CYP2C19GRIK1GRIK2CPA1ALDH1A1 | |
| SCHEMBL24215021 | 0.72 | GRIK1 (0.55) | CYP2C19GRIK1GRIK2CPA1MAPT | |
| SCHEMBL56402 | 0.72 | GRIK1 (0.55) | CYP2C19GRIK1GRIK2CPA1MAPT | |
| SCHEMBL7114024 | 0.72 | GRIK1 (0.55) | CYP2C19GRIK1GRIK2CPA1MAPT | |
| SCHEMBL6644938 | 0.71 | CYP2D6 (0.56) | CYP2D6CYP2C19ALDH1A1HPGDMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |
| EP-0815084-A1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | THE PROCTER & GAMBLE COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |
| WO-1996029313-A1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | THE PROCTER & GAMBLE COMPANY (US) | 1996-09-26 | — | — | WO | disclosed |