Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11398066 | 0.96 | TSHR (0.69) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Ethyl Ester SCHEMBL3395338 | 0.94 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Ethyl Ester SCHEMBL7182126 | 0.89 | TSHR (0.43) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| SCHEMBL28562411 | 0.87 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Ethyl Ester SCHEMBL3886301 | 0.86 | TSHR (0.47) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Ethyl Ester SCHEMBL10823318 | 0.84 | TSHR (0.88) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Ethyl Ester SCHEMBL27812800 | 0.84 | TSHR (0.88) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Ethyl Ester SCHEMBL23796 | 0.84 | TSHR (0.88) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylonitrile SCHEMBL9419944 | 0.84 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Ethyl Ester SCHEMBL3698296 | 0.84 | TSHR (0.69) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11043503-A | — | — | None | — | — | JP | disclosed |
| EP-0893456-B1 | Process for producing modified acrylic rubber | NIPPON MEKTRON KK (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-6380318-B1 | PEROXIDE CURABLE; SOLVENT-FREE | NIPPON MEKTRON, LIMITED (JP) | 2002-04-30 | — | — | US | disclosed |
| JP-H1143503-A | PRODUCTION OF MODIFIED ACRYLIC RUBBER | NIPPON MEKTRON LTD | 1999-02-16 | — | — | JP | disclosed |
| EP-0893456-A1 | Process for producing modified acrylic rubber | Nippon Mektron, Limited (JP) | 1999-01-27 | — | — | EP | disclosed |