Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 19/20 | 0.74 |
| ▸ | AVPR1A | P37288 | 8/20 | 0.54 |
| ▸ | OXTR | P30559 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperazine SCHEMBL7000607 | 0.94 | AVPR2 (0.66) | AVPR2AVPR1AOXTR | |
| SCHEMBL6999868 | 0.94 | AVPR2 (0.71) | AVPR2AVPR1AOXTR | |
| SCHEMBL7002070 | 0.89 | AVPR2 (0.82) | AVPR2AVPR1A | |
| SCHEMBL7092064 | 0.87 | AVPR2 (0.69) | AVPR2AVPR1AOXTR | |
| SCHEMBL6999482 | 0.85 | AVPR2 (0.71) | AVPR2AVPR1AOXTR | |
| SCHEMBL6997469 | 0.85 | AVPR2 (1.00) | AVPR2AVPR1A | |
| SCHEMBL7002078 | 0.84 | AVPR2 (0.72) | AVPR2AVPR1AOXTR | |
| Piperazine SCHEMBL7001718 | 0.84 | AVPR2 (0.74) | AVPR2AVPR1A | |
| SCHEMBL6994184 | 0.79 | AVPR2 (0.68) | AVPR2AVPR1A | |
| SCHEMBL6997117 | 0.78 | AVPR2 (1.00) | AVPR2AVPR1AOXTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021444-B1 | 3-CARBOXAMIDE DERIVATIVES OF 5H-PYRROLO[2,1-c][1,4]-BENZODIAZEPINES | WYETH CORP (US) | 2003-09-24 | — | — | EP | disclosed |