Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.77 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.59 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.59 |
| ▸ | FAP | Q12884 | 1/20 | 0.59 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095295 | 1.00 | DPP4 (0.77) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL7333825 | 0.95 | DPP4 (0.70) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL1723023 | 0.87 | DPP4 (1.00) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL1723024 | 0.87 | DPP4 (1.00) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL1723021 | 0.87 | DPP4 (1.00) | DPP4DPP8DPP9FAPDPP7 | |
| Hydrochloric Acid SCHEMBL2708883 | 0.86 | DPP4 (0.97) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL6167910 | 0.79 | DPP4 (0.85) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL1071023 | 0.78 | PREP (0.56) | DPP4DPP8DPP9 | |
| SCHEMBL9073810 | 0.77 | DPP4 (0.62) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL1798266 | 0.77 | DPP4 (0.62) | DPP4DPP8DPP9FAPDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1597697-A | Human parathyrin 1.34 peptide related peptide-Pro-Pro-[Arg11 hPTH (1.34)-Pro-Pro | CHINA MEDICINE UNIV (CN) | 2005-03-23 | — | — | CN | disclosed |
| US-6590078-B2 | Fusion proteins comprising signal amino acid sequences selected from glucoamylase, amylase, protease, chymosin or tissue plasminogen activator from aspergillus or tolypocladium | GENENCOR INTERNATIONAL, INC. | 2003-07-08 | — | — | US | disclosed |
| US-20030092131-A1 | DNA sequences, vectors, and fusion polypeptides for secretion of polypeptides in filamentous fungi | GENENCOR INTERNATIONAL, INC. | 2003-05-15 | — | — | US | disclosed |
| US-6265204-B1 | NUCLEIC ACID WHICH ENCODES A FUSION PROTEIN COMPRISED OF SIGNAL POLYPEPTIDE FOR SECRETION, SECRETED POLYPEPTIDE, CLEAVABLE LINKER, AND DESIRED POLYPEPTIDE; GENE EXPRESSION | GENENCOR INTERNATIONAL, INC. | 2001-07-24 | — | — | US | disclosed |
| WO-1998031821-A2 | DNA SEQUENCES, VECTORS, AND FUSION POLYPEPTIDES FOR SECRETION OF POLYPEPTIDES IN FILAMENTOUS FUNGI | GENENCOR INTERNATIONAL, INC. (US) | 1998-07-23 | — | — | WO | disclosed |